In this paper I attempt to show, against certain versions of trope theory, that properties with analyzable particularity cannot be merely exactly similar: such properties are either particularized properties (tropes) that are dissimilar to every any other trope, or else universalized properties (universals). I argue that each of the most viable standard and nonstandard particularizers that can be employed to secure the numerical difference between exactly similar properties can only succeed in grounding the particularity of properties, that is, in having (...) properties be tropes, at the expense of ruling out the possibility of their exact similarity. Here are the four nonstandard particularizers that I examine: the genealogy of a property, the history of a property, the causal effects of a property, and the duration of a property. And here are the two standard particularizers that I examine: the bearer of a property, by which I mean either a bare particular or a spatiotemporal location, and the property itself, by which I mean that the property is self-particularized. In my concluding remarks, I explain that the only remaining hope for preserving the possibility of exactly similar tropes is regarding properties as primitively particular, and that this must mean not that properties are selfparticularized but that they are particularized due to nothing. I close by arguing that this may not help trope theory after all. (shrink)

The goal of this paper is to figure out whether Aristotle's response to the argument for fatalism in De Interpretatione 9 is a success. By "response" it is meant not simply the reasons Aristotle offers to highlight why fatalism does not accord with how we conduct our lives, but also the solution he devises to block the argument for fatalism. This paper finds that a) Aristotle's argument for fatalism is essentially bivalence plus that the truth of a proposition implies necessity, (...) b) that Aristotle's solution is to restrict bivalence, c) that this solution is coherent, and d) that while this solution does not rule out the possibility of fatalism, it does succeed in blocking the argument for fatalism offered within chapter 9. El objetivo de este trabajo es esclarecer si la respuesta de Aristóteles al argumento a favor del fatalismo en De Interpretatione 9 resulta exitosa. Por "respuesta" se entienden no solo las razones que da Aristóteles para destacar porqué el fatalismo no concuerda con la manera en que llevamos nuestras vidas, sino también la solución que ofrece para bloquear el argumento a favor del fatalismo. El artículo plantea a) que el argumento de Aristóteles respecto del fatalismo consiste esencialmente en la bivalencia más el hecho de que la verdad de una proposición implica necesidad; b) que la solución de Aristóteles es restringir la bivalencia; c) que esta solución es coherente, y d) que si bien esta solución no elimina la posibilidad del fatalismo, sí logra bloquear el argumento a favor del fatalismo ofrecido en el capítulo 9. O objetivo deste trabalho é esclarecer se a resposta de Aristóteles ao argumento a favor do fatalismo em De Interpretatione 9 é bem-sucedida. Por "resposta" se entendem não somente as razões que Aristóteles dá para destacar por que o fatalismo não está de acordo com a maneira em que levamos nossas vidas, mas também a solução que oferece para bloquear o argumento a favor do fatalismo. Este artigo propõe que: a) o argumento de Aristóteles a respeito do fatalismo consiste essencialmente na bivalência mais o fato de que a verdade de uma proposição implica necessidade; b) a solução de Aristóteles é restringir a bivalência; c) essa solução é coerente, e d) embora essa solução não elimine a possiblidade do fatalismo, consegue bloquear o argumento a favor dele oferecido no capítulo 9. (shrink)

Some passages throughout Spinoza’s body of works suggest that an attribute in its absolute nature provides a sufficient condition for all of its modes, including the finite ones. Other passages suggest that an attribute in its absolute nature fails to provide a sufficient condition for its finite modes. My aim is to dispel this apparent tension. I argue that all finite modes are ultimately entailed by the absolute nature of their attribute. Furthermore, I explain how the Spinozistic positions that appear (...) incompatible with this view are in fact compatible. As I see it, we should read those passages where Spinoza says that no finite mode ultimately follows from the absolute nature of its attribute as saying merely that no finite mode ultimately follows in one-by-one fashion, independent of an infinite series of other modes, from the absolute nature of its attribute. (shrink)

We have compared two different laser-induced optical light traps for their utility in moving organelles within living animal cells and walled fungal cells. The first trap employed a continuous wave neodymium-yttrium aluminum garnet laser at a wavelength of 1.06 micron. A second trap was constructed using a titanium-sapphire laser tunable from 700 to 1000 nm. With the latter trap we were able to achieve much stronger traps with less laser power and without damage to either mitochondria or spindles. Chromosomes and (...) nuclei were easily displaced, nucleoli were separated and moved far away from interphase nuclei, and Woronin bodies were removed from septa. In comparison, these manipulations were not possible with the Nd-YAG laser-induced trap. The optical force trap induced by the tunable titanium-sapphire laser should find wide application in experimental cell biology because the wavelength can be selected for maximization of force production and minimization of energy absorption which leads to unwanted cell damage. (shrink)

Nature Network Groups hosted an invited workshop on 'Theories of Consciousness' during the second semester of 2009. There were presentations by each of 15 authors active in the field, followed by debate with other presenters and invitees. A week was allocated to each of the theories proposed; general discussion threads were also opened from time to time, as seemed appropriate. We offer here an account of the principal outcomes. It can be regarded as a contemporary, 'state of the art' snapshot (...) of thinking in this field. (shrink)

In this paper we scrutinize the so called Principle of Local Lorentz Invariance (PLLI) that many authors claim to follow from the Equivalence Principle. Using rigourous mathematics, we introduce in the General Theory of Relativity two classes of reference frames (PIRFs and LLRFγs) which as natural generalizations of the concept of the inertial reference frames of the Special Relativity Theory. We show that it is the class of the LLRFγs that is associated with the PLLI. Next we give a definition (...) of physically equivalent reference frames. Then, we prove that there are models of General Relativity Theory (in particular on a Friedmann universe) where the PLLI is false. However our finding is not in contradiction with the many experimental claims vindicating the PLLI, because theses experiments do not have enough accuracy to detect the effect we found. We prove moreover that PIRFs are not physically equivalent. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct.

My aim in the present paper is to show the significance of Heidegger's phenomenology of religion as an important step on his way to his magnum opus . First, I wish to exhibit traits characteristic of Heidegger's path of thinking in terms of his confrontation with phenomenology, historicism, hermeneutics, and Lebensphilosophie . I will then argue, in a second step, that it was with an eye to, and drawing upon, his previous understanding of religion and religious life, as well as (...) of the relation between faith and theology, that Heidegger was to conceive of philosophy and its relation to human existence in Being and Time . Both theology and philosophy offer a conceptual elaboration of something previously enacted or lived and, in doing so, are at the same time meant to refer back to and reinforce what they grow out of—faith or factical life. (shrink)

This papers deals with examples offered by Adams, Austin and others which seem to show that `if' does not conform to all of the laws of the conditional. These a reconciled by treating them as conjunctions with embedded modalities.

After recalling the rigorous mathematical representations in Relativity Theory (RT) of (i) observers, (ii) reference frames fields, (iii) their classifications, (iv) naturally adapted coordinate systems (nacs) to a given reference frame, (v) synchronization procedure and some other key concepts, we analyze three problems concerning experiments on rotating frames which even now (after almost a century after the birth of RT) are sources of misunderstandings and misconceptions. The first problem, which serves to illustrate the power of rigorous mathematical methods in RT, (...) is the explanation of the Sagnac effect (SE). This presentation is opportune because recently there have appeared many non sequitur claims in the literature stating that the SE cannot be explained by SRT, even disproving this theory or claiming that the explanation of the effect requires a new theory of electrodynamics. The second example has to do with the measurement of the one-way velocity of light in rotating reference frames, a problem about which many wrong statements appear in recent literature. The third problem has to do with claims that only Lorentz-like type transformations can be used between the nacs associated with a reference frame mathematically modeling of a rotating platform and the nacs associated with a inertial frame (the laboratory). We show that these claims are equivocal. (shrink)

The claim that there are significant parallels and connections between hermeneutics and humanism may be plausible from the mere fact that the magnum opus of contemporary hermeneutics, Gadamer's Truth and Method, opens with a chapter on “The significance of the humanist tradition for the human sciences”, which is discussed in this chapter. A brief interpretation of the Gadamer's chapter and its philosophical background will be followed by a short interpretive reconstruction of the origin and history of the concept of humanism (...) and its interconnections with hermeneutics. Possible or plausible consequences of what has been said include the following two theses: hermeneutics is humanism; and the contemporary form of humanism is hermeneutics. From this perspective, hermeneutics may be said to be the heir of the legacy of the humanist tradition and may be entitled to be called its form in the twentieth and twentieth‐first centuries more than any other philosophical stance. (shrink)

This chapter proposes to reconstruct and make sense of Gadamer's position with regard to the concept of prejudice in its relation to several neighboring, that is, related concepts. These concepts include, first of all, pre‐understanding.The method of clarifying the meaning of concepts through reconstruction of their history is based on a particular conviction or, more exactly speaking, a philosophical position. According to it, philosophical concepts are determined in their meaning not through a random choice to designate them with that word (...) “but rather on the basis of their historical background”, and “legitimate philosophizing needs to be able to account historically for its own concepts”. The chapter then shows how Gadamer's treatment of the issue was anticipated and indeed delineated by Heidegger. The particular prejudice we are urged to liberate ourselves from is the assumption that past ages knew better how things were than we do. (shrink)

The connections between hermeneutics and ontology cannot be restricted to the ontological (re)conception of understanding and interpretation. The ontological thematization of understanding and interpretation provided by Heidegger in Being and Time, is preceded by another, more original, and more comprehensive interrelation between hermeneutics and ontology. The former, the ontological thematization of understanding and interpretation may be seen to be, as it were, but a “derivative” case of this more primordial interdependence or fusion of ontology and hermeneutics which has always already (...) been operative or set into motion from the very first pages of the work in terms of a reciprocal dependence of the Being‐question (ontology) and a (vague and average) “understanding of Being” (hermeneutics). This chapter attempts to reconstruct and elaborate on the emergence of this twofold relation on Heidegger's path of thinking up to and inclusive of Being and Time. (shrink)

Aristotle asserts at 1073b10-13 that he intends to give in Metaphysics XII.8 a definite conception about the multitude of the divine transcendent entities, which function as the movers of the celestial spheres. In order to do so, he describes several celestial theories. First Eudoxus’s, then the modifications of this theory propounded by Callippus, and finally his own suggestion, the introduction of yet further spheres which integrate the celestial spheres into a single overarching scheme. For this, after explaining the spheres providing (...) the component motions of each planet, Aristotle introduces so-called rewinding spheres (anelittousai), which perform contrary revolutions to the ones performed by the spheres carrying the planet. (shrink)

PURPOSE:To report the localization of a gene causing drusen and macular degeneration in a previously undescribed North American family. METHODS:Genetic mapping studies were performed using linkage analysis in a single family with drusen and atrophic macular degeneration. RESULTS:The clinical manifestations in this family ranged from fine macular drusen in asymptomatic middle-aged individuals to atrophic macular lesions in two children and two elderly patients. We mapped the gene to chromosome 6q14 between markers D6S2258 and D6S1644. CONCLUSIONS:In a family with autosomal dominant (...) drusen and atrophic macular degeneration, the gene maps to a 3.2-cM region on chromosome 6q14. This locus appears to be distinct from, but adjacent to, the loci for cone-rod dystrophy 7 (CORD7) and North Carolina macular dystrophy (MCDR1). Future identification of the gene responsible for the disease in this family will provide a better understanding of macular degeneration. (shrink)

Anaximander is the first philosopher whose theory of the heavens is preserved in broad outlines. According to the sources the celestial bodies are huge rings of compressed air around the earth, each visible only where it is perforated by a tubular vent through which the fire contained in it can shine. Greatest and farthest of them is the sun, next comes the moon and under them there is the ring of the stars. It is a common practice to put and (...) answer the following questions: ‘…why he should have placed the stellar circles or rings closer to the earth than are the sun and the moon.’ ‘…why these lower rings of stellar ρ do not obscure the brighter but more distant bodies.’. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Die Vorsokratiker: Ein philosophisches Portrȧt by Thomas BuchheimIstván BodnárThomas Buchheim. Die Vorsokratiker: Ein philosophisches Portrȧt. München: C.H. Beck, 1994. Pp. 262. Paper, DM 48.00.This book is a continuous narrative of highlights of presocratic philosophy. The vista offered by Buchheim is revisionary. The presocratics are behind a curve of the road of the philosophical enterprise. What we usually perceive is a mirage created by the doxographic tradition, emanating ultimately (...) from Aristotle. This much might be uncontroversial: the history of presocratic philosophy has been for the last two centuríes a continuous effort to liberate the remains of those early philosophers from the imputations of later authors. But Buchheim’s project is more ambitious than our ordinary occupation with the presocratics. He postulates a specific, markedly presocratic type of appropriation of the world, and then uses this as a yardstick to elicit a new understanding of the mutilated body of the early texts. Presocratic thought is not theoretical, but rather reactive; it cannot extricate itself from the situation in which it is directed at its object.While some of his discussion is perceptive, the chapters abound in idiosyncratic interpretations. It will suffice to mention only a few of Buchheim’s central claims by way of illustration. Although it has been widely held that Anaximander’s apeiron is not only boundless, but also indefinite, Buchheim’s contention that it should be seen as a disorienting and chaotic matrix which provides no foothold for the discerning and distinguishing mind overshoots the mark. This claim does not mesh well with the allowance in Anaximander that there can be a plurality of simultaneous worlds. There can be a disorienting extension beyond the single cosmos, but several (and as some testimonies would claim, evenly distanced) worlds cannot possibly be separated by a medium which defies the notion of extension altogether.Few will be convinced by Buchheim’s claim that Heraclitus did not formulate a doctrine of opposites because he, coming before Parmenides, could have had only a conception of “counteractive parties in an originally unifying contention” (82), since Heraclitus’ provocative pronouncements would thereby be diluted into mere platitudes. Since Empedocles never calls his rhizömata elements, Buchheim impugns the Empedoclean origin of the four element doctrine. For this he needs to explain away much of the evidence of the fragments. Some of the images Empedocles deploys would suggest a mere juxtaposition of the ingredients, some might indicate some more intimate bond arising between these. As Buchheim aptly notes, the choice in this matter is not obvious. Nevertheless there are places where Buchheim’s interpretation is at a serious disadvantage. Empedocles B8, on the standard reading would rule out the [End Page 521] notion of a phusis (growth, generation) or teleutë- (end, perishing) of any mortal thing, and would allow for the mixιs (mixing) and diallaxιs (separation) of what is mixed together. Immortal things, devoid of generation and perishing by default, are understandably not taken into account here. On Buchheim’s reading, however, Empedoclean rhizömata would be allowed to grow, and hence, by a similar reasoning, to perish.In Chapter 5, Buchheim accuses Aristotle of systematically replacing the dynamically loaded expressions of the ancient atomists, characterizing the ultimate building blocks of nature, with static, geometric idioms. The sole exception where Aristotle does not rob the atomists of this dynamic conception of atomic nature, Buchheim claims, is Physics 8.9 265b23ff. But the uniqueness of the passage rests on Buchheim’s idiosyncratic translation. On the standard interpretation (going back at least to Simplicius) Aristotle asserts only that, according to the atomists, nature performs local motion, and not—as Buchheim would have it—that the nature of the atoms is the very performing of local motion.Contrary to Buchheim’s general characterization of presocratic thought as imbued or integrated with the circumstances of cognition, Anaxagoras’ nous is pure and distinct, not mixed with any other ingredient of the universe. For this reason, Buchheim in his final chapter presents Anaxagoras as a transitional figure between presocratic thought and later, classical metaphysics. The details of this claim, just like the overall characterization of the presocratics, are bound... (shrink)

Saving the appearances (sôzein ta phainomena) often features as a programmatic description of the aim and objective of ancient astronomical theory. The paper, after an expository section, discusses some earlier proposals for what such a programme presupposes. After this, through a survey of the usage in Plato and Aristotle of some key terms—among them the verb sôzein—describing the relationship of an account to what it is an account of, submits that the phrase in this semantic framework could express the crucial (...) property of an account that it is faithful to the phenomena, and it does not overrule or discard them. (shrink)

This paper attempts to outline some of the important concepts and ideas used in system analysis which is taken to be a general mode of analysis used in all sciences. Systems are seen from three perspectives: (1) that involving the relationship between system and environment, (2) that involving interaction between several systems, and (3) that involving one type of system composed of other types of systems. The writers also discuss the concepts "structure" and "equilibrium" as they apply to system analysis, (...) the point being made that the use of these concepts in the social sciences has often been vague or even incorrect. (shrink)